Analysis of the p53 pathway in peripheral blood of retinoblastoma patients; potential biomarkers.

Loss of retinoblastoma (RB) function in the cone cells during retina development is necessary but not sufficient for retinoblastoma development. It has been reported that in the absence of RB activity, a retinoma is generated, and the onset of retina cancer occurs until the p53 pathway is altered. U...

Full description

Bibliographic Details
Main Authors: Mayra Martínez-Sánchez, Mariana Moctezuma-Dávila, Jesús Hernandez-Monge, Martha Rangel-Charqueño, Vanesa Olivares-Illana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0234337