Focal epileptiform activity in the prefrontal cortex is associated with long-term attention and sociability deficits

Focal epileptiform activity in the prefrontal cortex is associated with long-term attention and sociability deficits

There is a well-described association between childhood epilepsy and pervasive cognitive and behavioral deficits. Often these children not only have ictal EEG events, but also frequent interictal abnormalities. The precise role of these interictal discharges in cognition remains unclear. In order to...

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Bibliographic Details
Main Authors: Amanda E. Hernan, Abigail Alexander, Kyle R. Jenks, Jeremy Barry, Pierre-Pascal Lenck-Santini, Elena Isaeva, Gregory L. Holmes, Rod C. Scott
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Neurobiology of Disease
Subjects:
Pediatric epilepsy
Interictal spikes
Attention
Social behavior
Short-term plasticity
Prefrontal cortex
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113003240

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http://www.sciencedirect.com/science/article/pii/S0969996113003240

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