miR-127 protects proximal tubule cells against ischemia/reperfusion: identification of kinesin family member 3B as miR-127 target.

Ischemia/reperfusion (I/R) is at the basis of renal transplantation and acute kidney injury. Molecular mechanisms underlying proximal tubule response to I/R will allow the identification of new therapeutic targets for both clinical settings. microRNAs have emerged as crucial and tight regulators of...

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Main Authors: Elia Aguado-Fraile, Edurne Ramos, David Sáenz-Morales, Elisa Conde, Ignacio Blanco-Sánchez, Konstantinos Stamatakis, Luis del Peso, Edwin Cuppen, Bernhard Brüne, María Laura García Bermejo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3433485?pdf=render