The Abi-domain protein Abx1 interacts with the CovS histidine kinase to control virulence gene expression in group B Streptococcus.

Group B Streptococcus (GBS), a common commensal of the female genital tract, is the leading cause of invasive infections in neonates. Expression of major GBS virulence factors, such as the hemolysin operon cyl, is regulated directly at the transcriptional level by the CovSR two-component system. Usi...

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Bibliographic Details
Main Authors: Arnaud Firon, Asmaa Tazi, Violette Da Cunha, Sophie Brinster, Elisabeth Sauvage, Shaynoor Dramsi, Douglas T Golenbock, Philippe Glaser, Claire Poyart, Patrick Trieu-Cuot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-02-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23436996/pdf/?tool=EBI