Interleukin 4 induces transcription of the 15-lipoxygenase I gene in human endothelial cells

Interleukin 4 induces transcription of the 15-lipoxygenase I gene in human endothelial cells

The reticulocyte-type 15-lipoxygenase (15-LO-I) has been implicated in atherogenesis because of its capability of oxidizing low density lipoprotein. Therefore, we investigated the expression of the 15-LO-I gene in human umbilical vein endothelial cells (HUVEC). Nonactivated HUVEC did not exhibit det...

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Bibliographic Details
Main Authors: Yong Woo Lee, Hartmut Kühn, Simone Kaiser, Bernhard Hennig, Alan Daugherty, Michal Toborek
Format: Article
Language:English
Published: Elsevier 2001-05-01
Series:Journal of Lipid Research
Subjects:
cytokines
atherosclerosis
oxidation
transcriptional regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520316412

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http://www.sciencedirect.com/science/article/pii/S0022227520316412

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