IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study.

In an ongoing clinical phase I/II study, 16 pediatric patients suffering from high risk leukemia/tumors received highly purified donor natural killer (NK) cell immunotherapy (NK-DLI) at day (+3) +40 and +100 post haploidentical stem cell transplantation. However, literature about the influence of NK...

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Main Authors: Claudia Brehm, Sabine Huenecke, Andrea Quaiser, Ruth Esser, Melanie Bremm, Stephan Kloess, Jan Soerensen, Hermann Kreyenberg, Christian Seidl, Petra S A Becker, Heiko Mühl, Thomas Klingebiel, Peter Bader, Jakob R Passweg, Dirk Schwabe, Ulrike Koehl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3212563?pdf=render