Mitomycin C Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes via a Mitochondrial-Mediated Pathway

Mitomycin C Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes via a Mitochondrial-Mediated Pathway

Background/Aims: Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease characterised by prominent synoviocyte hyperplasia and a potential imbalance between the growth and death of fibroblast-like synoviocytes (FLS). Mitomycin C (MMC) has previously been demonstrated to inhibit fibrobl...

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Bibliographic Details
Main Authors: Chuqi Yan, Dechao Kong, Dong Ge, Yanming Zhang, Xishan Zhang, Changhui Su, Xiaojian Cao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Mitomycin C
Rheumatoid arthritis
Mitochondrial pathway
Fibroblast-like synoviocytes
Apoptosis
Online Access:http://www.karger.com/Article/FullText/373938

Internet

http://www.karger.com/Article/FullText/373938

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