Hydrogen Peroxide Induce Human Cytomegalovirus Replication through the Activation of p38-MAPK Signaling Pathway

Hydrogen Peroxide Induce Human Cytomegalovirus Replication through the Activation of p38-MAPK Signaling Pathway

Human cytomegalovirus (HCMV) is a major risk factor in transplantation and AIDS patients, which induces high morbidity and mortality. These patients infected with HCMV experience an imbalance of redox homeostasis that cause accumulation of reactive oxygen species (ROS) at the cellular level. H2O2, t...

Full description

Bibliographic Details
Main Authors: Jun Xiao, Jiang Deng, Liping Lv, Qiong Kang, Ping Ma, Fan Yan, Xin Song, Bo Gao, Yanyu Zhang, Jinbo Xu
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Viruses
Subjects:
CMV
H2O2
IE1
viral replication
antioxidants
p38-MAPK
Online Access:http://www.mdpi.com/1999-4915/7/6/2748

Internet

http://www.mdpi.com/1999-4915/7/6/2748

Similar Items