Blocking CD47 efficiently potentiated therapeutic effects of anti-angiogenic therapy in non-small cell lung cancer

Blocking CD47 efficiently potentiated therapeutic effects of anti-angiogenic therapy in non-small cell lung cancer

Abstract Background Inhibitors targeting VEGF and VEGFR are commonly used in the clinic, but only a subset of patients could benefit from these inhibitors and the efficacy was limited by multiple relapse mechanisms. In this work, we aimed to investigate the role of innate immune response in anti-ang...

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Bibliographic Details
Main Authors: Xuyao Zhang, Yichen Wang, Jiajun Fan, Wei Chen, Jingyun Luan, Xiaobin Mei, Shaofei Wang, Yubin Li, Li Ye, Song Li, Wenzhi Tian, Kai Yin, Dianwen Ju
Format: Article
Language:English
Published: BMJ Publishing Group 2019-12-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Anti-angiogenesis
VEGF
CD47
Immunotherapy
Bispecific therapy
Online Access:http://link.springer.com/article/10.1186/s40425-019-0812-9

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http://link.springer.com/article/10.1186/s40425-019-0812-9

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