Microfluidic purification and concentration of malignant pleural effusions for improved molecular and cytomorphological diagnostics.

Evaluation of pleural fluids for metastatic cells is a key component of diagnostic cytopathology. However, a large background of smaller leukocytes and/or erythrocytes can make accurate diagnosis difficult and reduce specificity in identification of mutations of interest for targeted anti-cancer the...

Full description

Bibliographic Details
Main Authors: James Che, Albert J Mach, Derek E Go, Ish Talati, Yong Ying, Jianyu Rao, Rajan P Kulkarni, Dino Di Carlo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3810139?pdf=render