Toxic Responses Induced at High Doses May Affect Benchmark Doses
To derive reference points (RPs) for health-based guidance values, the benchmark dose (BMD) approach increasingly replaces the no-observed-adverse-effect level approach. In the BMD approach, the RP corresponds to the benchmark dose lower confidence bounds (BMDLs) of a mathematical dose–response mode...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2020-04-01
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| Series: | Dose-Response |
| Online Access: | https://doi.org/10.1177/1559325820919605 |