Comparison of CD8+ T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria

Comparison of CD8+ T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria

CD8+ T cells have been shown to play a critical role in the pathogenesis of experimental cerebral malaria (ECM) in mice, but their role in development of human cerebral malaria (HCM) remains unclear. Thus, in this study we have provided the first direct contrast of the accumulation of CD8+ T cells i...

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Bibliographic Details
Main Authors: Valentina Barrera, Michael J. Haley, Patrick Strangward, Elizabeth Attree, Steve Kamiza, Karl B. Seydel, Terrie E. Taylor, Danny A. Milner, Alister G. Craig, Kevin N. Couper
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
cerebral malaria
CD8+ T cells
brain
Plasmodium falciparum
Plasmodium berghei
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01747/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01747/full

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