Determination of circuit-specific morphological adaptations in ventral tegmental area dopamine neurons by chronic morphine

Abstract Chronic opiate exposure induces neuroadaptations in the mesocorticolimbic system including ventral tegmental area (VTA) dopamine (DA) neurons, whose soma size is decreased following opiate exposure. Yet it is now well documented that VTA DA neurons are heterogeneous, with notable difference...

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Bibliographic Details
Main Authors: Sarah C. Simmons, Katie Wheeler, Michelle S. Mazei-Robison
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-019-0435-6