Comparison of desferrioxamine and NODAGA for the gallium-68 labeling of exendin-4

Comparison of desferrioxamine and NODAGA for the gallium-68 labeling of exendin-4

Abstract Introduction Radiolabeled exendin-4 (Ex4) derivatives are used to target the glucagon-like peptide-1 receptor (GLP-1R) for the clinical diagnosis of insulinomas, a rare type of neuroendocrine tumor. Gallium-68 is an ideal diagnostic nuclide for this application and a study evaluating an exe...

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Bibliographic Details
Main Authors: Simon A. M. Kaeppeli, Roger Schibli, Thomas L. Mindt, Martin Behe
Format: Article
Language:English
Published: SpringerOpen 2019-05-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Exendin-4
β-cells
Insulinoma
GLP-1R
NODAGA
DFO
Online Access:http://link.springer.com/article/10.1186/s41181-019-0060-9

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http://link.springer.com/article/10.1186/s41181-019-0060-9

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