MAVS-mediated apoptosis and its inhibition by viral proteins.

<h4>Background</h4>Host responses to viral infection include both immune activation and programmed cell death. The mitochondrial antiviral signaling adaptor, MAVS (IPS-1, VISA or Cardif) is critical for host defenses to viral infection by inducing type-1 interferons (IFN-I), however its...

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Bibliographic Details
Main Authors: Yu Lei, Chris B Moore, Rachael M Liesman, Brian P O'Connor, Daniel T Bergstralh, Zhijian J Chen, Raymond J Pickles, Jenny P-Y Ting
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19404494/pdf/?tool=EBI