The expression of the Slit-Robo signal in the retina of diabetic rats and the vitreous or fibrovascular retinal membranes of patients with proliferative diabetic retinopathy.

The Slit-Robo signal has an important role in vasculogenesis and angiogenesis. Our study examined the expression of Slit2 and its receptor, Robo1, in a rat model of streptozotocin-induced diabetes and in patients with proliferative diabetic retinopathy.Diabetes was induced in male Sprague-Dawley rat...

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Bibliographic Details
Main Authors: Weiyan Zhou, Hongya Wang, Wenzhen Yu, Wankun Xie, Min Zhao, Lvzhen Huang, Xiaoxin Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5626485?pdf=render