Validation of near infrared fluorescence (NIRF) probes in vivo with dual laser NIRF endoscope.

PURPOSE:The development of NIRF cathepsin activity probes offered the ability to visualize tumor associated tumor reaction and act as a surrogate marker to delineate the dysplastic lesions. One major type is a NIRF substrate of cathepsins (SBP), which is involved in catalytic way to produce high lev...

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Bibliographic Details
Main Authors: Manisha Shrivastav, Elias Gounaris, Mohammad W Khan, Jeffrey Ko, Stacy H Ryu, Matthew Bogyo, Andrew Larson, Terrence A Barret, David J Bentrem
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6214553?pdf=render