Hypertension and genetic variation in endothelial-specific genes.

Genome-wide association (GWA) studies usually detect common genetic variants with low-to-medium effect sizes. Many contributing variants are not revealed, since they fail to reach significance after strong correction for multiple comparisons. The WTCCC study for hypertension, for example, failed to...

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Bibliographic Details
Main Authors: Erik Larsson, Björn Wahlstrand, Bo Hedblad, Thomas Hedner, Sverre E Kjeldsen, Olle Melander, Per Lindahl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3639261?pdf=render