The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer?

<p>Abstract</p> <p>The ADAMs are transmembrane proteins implicated in proteolysis and cell adhesion. Forty gene members of the family have been identified, of which 21 are believed to be functional in humans. As proteases, their main substrates are the ectodomains of other transmem...

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Bibliographic Details
Main Authors: Duffy Michael J, Mullooly Maeve, O'Donovan Norma, Sukor Sumainizah, Crown John, Pierce Aisling, McGowan Patricia M
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Clinical Proteomics
Online Access:http://www.clinicalproteomicsjournal.com/content/8/1/9