Ni-Catalyzed Homoallylation of Polyhydroxy N,O-Acetals with Conjugated Dienes Promoted by Triethylborane

Ni-Catalyzed Homoallylation of Polyhydroxy N,O-Acetals with Conjugated Dienes Promoted by Triethylborane

In the presence of Ni-catalyst and triethylborane, N,O-acetals prepared from glycolaldehyde and glyceraldehyde with primary amines in situ underwent homoallylation with conjugated dienes to provide 2-amino-5-hexenols in high regio- and stereoselectivity. Under similar reaction conditions, N,O-acetal...

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Bibliographic Details
Main Authors: Takamichi Mori, Yusuke Akioka, Gen Onodera, Masanari Kimura
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Molecules
Subjects:
nickel
homoallylation
N,O-acetal
carbohydrate
conjugated diene
triethylborane
reductive coupling
Online Access:http://www.mdpi.com/1420-3049/19/7/9288

Internet

http://www.mdpi.com/1420-3049/19/7/9288

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