Free Water in White Matter Differentiates MCI and AD From Control Subjects

Recent evidence shows that neuroinflammation plays a role in many neurological diseases including mild cognitive impairment (MCI) and Alzheimer's disease (AD), and that free water (FW) modeling from clinically acquired diffusion MRI (DTI-like acquisitions) can be sensitive to this phenomenon. T...

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Bibliographic Details
Main Authors: Matthieu Dumont, Maggie Roy, Pierre-Marc Jodoin, Felix C. Morency, Jean-Christophe Houde, Zhiyong Xie, Cici Bauer, Tarek A. Samad, Koene R. A. Van Dijk, James A. Goodman, Maxime Descoteaux, Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00270/full