Mapping Autoantibodies in Children With Acute Rheumatic Fever

Mapping Autoantibodies in Children With Acute Rheumatic Fever

BackgroundAcute rheumatic fever (ARF) is a serious sequela of Group A Streptococcus (GAS) infection associated with significant global mortality. Pathogenesis remains poorly understood, with the current prevailing hypothesis based on molecular mimicry and the notion that antibodies generated in resp...

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Bibliographic Details
Main Authors: Reuben McGregor, Mei Lin Tay, Lauren H. Carlton, Paulina Hanson-Manful, Jeremy M. Raynes, Wasan O. Forsyth, Diane T. Brewster, Martin J. Middleditch, Julie Bennett, William John Martin, Nigel Wilson, Polly Atatoa Carr, Michael G. Baker, Nicole J. Moreland
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
autoantibody
rheumatic fever
protein array
immunoassay
autoantigen
streptococcus A
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.702877/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.702877/full

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