Identification of the Alternative Splicing of the UL49 Locus of Human Cytomegalovirus

The UL49 ORF of human cytomegalovirus (HCMV) is essential for viral replication; conserved among all herpes viruses; however, the function is unclear. Once the UL49 ORF was precisely deleted from the start to stop codon, the mutant did not yield infectious progeny. In this study, we find out many al...

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Bibliographic Details
Main Authors: Guang Yang, Wei Li, Wenzhen Liao, Xin Zhang, Yi Zou, Jianfeng Dai, Yueqin Li, Chunxia Jing, Tianhong Zhou
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/280276