Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD
<p>Abstract</p> <p>Background</p> <p>Chronic Obstructive Pulmonary Disease (COPD) is characterized by defective extracellular matrix (ECM) turnover as a result of prolonged cigarette smoking. Fibroblasts have a central role in ECM turnover. The TGFβ induced Smad pathway...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-12-01
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| Series: | Respiratory Research |
| Online Access: | http://respiratory-research.com/content/9/1/83 |