Rapamycin Modulates the Proinflammatory Memory-Like Response of Microglia Induced by BAFF

Rapamycin Modulates the Proinflammatory Memory-Like Response of Microglia Induced by BAFF

BackgroundRecently trained immunity of microglia provided an opportunity to study the chronic effect of microglial activation and its metabolic rewiring in neuroimmunological diseases. Since elevated levels of B cell-activating factor (BAFF) have been proved to be associated with some chronic neuroi...

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Bibliographic Details
Main Authors: Jianing Wang, Chunshu Yang, Xiaoyu Hou, Jingyi Xu, Yang Yun, Ling Qin, Pingting Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
B cell-activating factor
microglia
trained immunity
aerobic glycolysis
mammalian target of rapamycin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.639049/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.639049/full

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