A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains

A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains

Abstract Background Partially methylated domains are extended regions in the genome exhibiting a reduced average DNA methylation level. They cover gene-poor and transcriptionally inactive regions and tend to be heterochromatic. We present a comprehensive comparative analysis of partially methylated...

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Bibliographic Details
Main Authors: Abdulrahman Salhab, Karl Nordström, Gilles Gasparoni, Kathrin Kattler, Peter Ebert, Fidel Ramirez, Laura Arrigoni, Fabian Müller, Julia K. Polansky, Cristina Cadenas, Jan G.Hengstler, Thomas Lengauer, Thomas Manke, DEEP Consortium, Jörn Walter
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Genome Biology
Subjects:
Partially methylated domains
Heterochromatin
Replication timing
Proliferation
Online Access:http://link.springer.com/article/10.1186/s13059-018-1510-5

Internet

http://link.springer.com/article/10.1186/s13059-018-1510-5

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