Yeast phosphatidic acid phosphatase Pah1 hops and scoots along the membrane phospholipid bilayer

PA phosphatase, encoded by PAH1 in the yeast Saccharomyces cerevisiae, catalyzes the Mg2+-dependent dephosphorylation of PA, producing DAG at the nuclear/ER membrane. This enzyme plays a major role in triacylglycerol synthesis and in the regulation of phospholipid synthesis. As an interfacial enzyme...

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Bibliographic Details
Main Authors: Joanna M. Kwiatek, George M. Carman
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520434911