Anaplasma phagocytophilum Ats-1 is imported into host cell mitochondria and interferes with apoptosis induction.

Anaplasma phagocytophilum, the causative agent of human granulocytic anaplasmosis, infects human neutrophils and inhibits mitochondria-mediated apoptosis. Bacterial factors involved in this process are unknown. In the present study, we screened a genomic DNA library of A. phagocytophilum for effecto...

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Bibliographic Details
Main Authors: Hua Niu, Vera Kozjak-Pavlovic, Thomas Rudel, Yasuko Rikihisa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2824752?pdf=render