Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross.

The extent and strength of epistasis is commonly unresolved in genetic studies, and observed epistasis is often difficult to interpret in terms of biological consequences or overall genetic architecture. We investigated the prevalence and consequences of epistasis by analyzing four body composition...

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Bibliographic Details
Main Authors: Anna L Tyler, Leah Rae Donahue, Gary A Churchill, Gregory W Carter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4734753?pdf=render