Foam Cells Control Mycobacterium tuberculosis Infection

Foam Cells Control Mycobacterium tuberculosis Infection

Mycobacterium tuberculosis (Mtb) infects macrophages and macrophage-derived foam cells, a hallmark of granulomata in tuberculous lesions. We analyzed the effects of lipid accumulation in human primary macrophages and quantified strong triglyceride and phospholipid remodeling which depended on the di...

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Bibliographic Details
Main Authors: Pooja Agarwal, Theo W. Combes, Fariba Shojaee-Moradie, Barbara Fielding, Siamon Gordon, Valerie Mizrahi, Fernando O. Martinez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Microbiology
Subjects:
tuberculosis
foam cells
macrophage
lipid droplets
cytokines
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01394/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01394/full

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