Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation

Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation

Summary: Synaptic structural plasticity, key to long-term memory storage, requires translation of localized RNAs delivered by long-distance transport from the neuronal cell body. Mechanisms and regulation of this system remain elusive. Here, we explore the roles of KIF5C and KIF3A, two members of ki...

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Bibliographic Details
Main Authors: Supriya Swarnkar, Yosef Avchalumov, Isabel Espadas, Eddie Grinman, Xin-an Liu, Bindu L. Raveendra, Aya Zucca, Sonia Mediouni, Abhishek Sadhu, Susana Valente, Damon Page, Kyle Miller, Sathyanarayanan V. Puthanveettil
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
local translation
RNA transport
learning and memory
synaptic transmission
structural plasticity
molecular motor proteins
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721007671

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http://www.sciencedirect.com/science/article/pii/S2211124721007671

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