Targeting smooth muscle cell phenotypic switching in vascular disease

Targeting smooth muscle cell phenotypic switching in vascular disease

Objective: The phenotypic plasticity of vascular smooth muscle cells (VSMCs) is central to vessel growth and remodeling, but also contributes to cardiovascular pathologies. New technologies including fate mapping, single cell transcriptomics, and genetic and pharmacologic inhibitors have provided fu...

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Bibliographic Details
Main Authors: Raja Chakraborty, PhD, Payel Chatterjee, PhD, Jui M. Dave, PhD, Allison C. Ostriker, PhD, Daniel M. Greif, MD, Eva M. Rzucidlo, MD, Kathleen A. Martin, PhD
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:JVS - Vascular Science
Subjects:
Smooth muscle
Intimal hyperplasia
Restenosis
Atherosclerosis
Differentiation
Phenotypic modulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666350321000080

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http://www.sciencedirect.com/science/article/pii/S2666350321000080

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