Oral Administration of Polymyxin B Modulates the Activity of Lipooligosaccharide E. coli B against Lung Metastases in Murine Tumor Models.

Oral Administration of Polymyxin B Modulates the Activity of Lipooligosaccharide E. coli B against Lung Metastases in Murine Tumor Models.

INTRODUCTION:Polymyxin B (PmB) belongs to the group of cyclic peptide antibiotics, which neutralize the activity of LPS by binding to lipid A. The aim of this study was to analyze the effect of PmB on the biological activity of lipooligosaccharide (LOS E. coli B,rough form of LPS) in vitro and in ex...

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Main Authors: Jagoda Kicielińska, Agnieszka Szczygieł, Joanna Rossowska, Natalia Anger, Katarzyna Kempińska, Marta Świtalska, Marta Kaszowska, Joanna Wietrzyk, Janusz Boratyński, Elżbieta Pajtasz-Piasecka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4735115?pdf=render

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http://europepmc.org/articles/PMC4735115?pdf=render

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