Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody.

Neisserial heparin binding antigen (NHBA) is one of three main recombinant protein antigens in 4CMenB, a vaccine for the prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup B. NHBA is a surface-exposed lipoprotein composed of a predicted disordered N-terminal regi...

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Bibliographic Details
Main Authors: Martina Maritan, Daniele Veggi, Roberta Cozzi, Lucia Dello Iacono, Erika Bartolini, Paola Lo Surdo, Giulietta Maruggi, Glen Spraggon, Matthew J Bottomley, Enrico Malito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6104945?pdf=render