Anti-cryptococcal activity of ethanol crude extract and hexane fraction from Ocimum basilicum var. Maria bonita: mechanisms of action and synergism with amphotericin B and Ocimum basilicum essential oil

Anti-cryptococcal activity of ethanol crude extract and hexane fraction from Ocimum basilicum var. Maria bonita: mechanisms of action and synergism with amphotericin B and Ocimum basilicum essential oil

Context: Ocimum basilicum L. (Lamiaceae) has been used in folk medicine to treat headaches, kidney disorders, and intestinal worms. Objective: This study evaluates the anti-cryptococcal activity of ethanol crude extract and hexane fraction obtained from O. basilicum var. Maria Bonita leaves. Materia...

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Bibliographic Details
Main Authors: Nathalia N. R. Cardoso, Celuta S. Alviano, Arie F. Blank, Maria de Fátima Arrigoni-Blank, Maria Teresa V. Romanos, Marcel M. L. Cunha, Antonio Jorge R. da Silva, Daniela S. Alviano
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Pharmaceutical Biology
Subjects:
basil
antifungal activity
cryptococcus neoformans
drug synergism
ergosterol
Online Access:http://dx.doi.org/10.1080/13880209.2017.1302483

Internet

http://dx.doi.org/10.1080/13880209.2017.1302483

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