TAM Receptor Inhibition–Implications for Cancer and the Immune System

Tyro3, Axl and MerTK (TAM) receptors are receptor tyrosine kinases which play important roles in efferocytosis and in the balancing of immune responses and inflammation. TAM receptor activation is induced upon binding of the ligands protein S (Pros1) or growth arrest-specific protein 6 (Gas6) which...

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Bibliographic Details
Main Authors: Pia Aehnlich, Richard Morgan Powell, Marlies J. W. Peeters, Anne Rahbech, Per thor Straten
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
Axl
Online Access:https://www.mdpi.com/2072-6694/13/6/1195