A Screen for Small Molecules to Target <i>Candida albicans</i> Biofilms

The human fungal pathogen <i>Candida albicans</i> can form biofilms on biotic and abiotic surfaces, which are inherently resistant to antifungal drugs. We screened the Chembridge Small Molecule Diversity library containing 30,000 “drug-like” small molecules and identified 45 compounds th...

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Bibliographic Details
Main Authors: Matthew B. Lohse, Craig L. Ennis, Nairi Hartooni, Alexander D. Johnson, Clarissa J. Nobile
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Journal of Fungi
Subjects:
Online Access:https://www.mdpi.com/2309-608X/7/1/9