Topotecan Delivery to the Optic Nerve after Ophthalmic Artery Chemosurgery.

Extraocular retinoblastoma is a major challenge worldwide, especially in developing countries. Current treatment involves the administration of systemic chemotherapy combined with radiation, but there is a clear need for improvement of chemotherapy bioavailability in the optic nerve. Our aim was to...

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Bibliographic Details
Main Authors: Paula Taich, Flavio Requejo, Marcelo Asprea, Mariana Sgroi, Pierre Gobin, David H Abramson, Guillermo Chantada, Paula Schaiquevich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4784825?pdf=render