FOXF2 reprograms breast cancer cells into bone metastasis seeds
Bone metastasis in breast cancer patients causes major skeletal-related complications. Here, the authors show that FOXF2/BMP/SMAD pathway plays a major role in bone metastasis and suggest targeting this axis to manage bone metastasis.
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2019-06-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-10379-7 |