Mycobacterium tuberculosis epitope-specific interferon-g production in healthy Brazilians reactive and non-reactive to tuberculin skin test

Mycobacterium tuberculosis epitope-specific interferon-g production in healthy Brazilians reactive and non-reactive to tuberculin skin test

The interferon (IFN)-γ response to peptides can be a useful diagnostic marker of Mycobacterium tuberculosis (MTB) latent infection. We identified promiscuous and potentially protective CD4+ T-cell epitopes from the most conserved r...

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Bibliographic Details
Main Authors: Bosco Christiano Maciel da Silva, Maria Fernanda Rios Grassi, Raimundo Coutinho, Rita Elizabeth Moreira Mascarenhas, Viviana Nilla Olavarria, Adriana Coutinho-Borgo, Jorge Kalil, Edecio Cunha Neto, Simone Gonçalves Fonseca
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2014-12-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Mycobacterium tuberculosis
epitopes
IFN-γ ELISPOT
latent tuberculosis
Mantoux tuberculin skin test
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000800999&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000800999&lng=en&tlng=en

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