Mechanism of Paeoniae Radix Alba in the Treatment of Non-alcoholic Fatty Liver Disease Based on Sequential Metabolites Identification Approach, Network Pharmacology, and Binding Affinity Measurement

Mechanism of Paeoniae Radix Alba in the Treatment of Non-alcoholic Fatty Liver Disease Based on Sequential Metabolites Identification Approach, Network Pharmacology, and Binding Affinity Measurement

Screening functional food ingredients (FFI) from medicinal and edible plants (MEP) has still remained a great challenge due to the complexity of MEP and its obscure function mechanisms. Herein, an integrated strategy based on sequential metabolites identification approach, network pharmacology, mole...

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Bibliographic Details
Main Authors: Zhiqiang Luo, Yang Liu, Xing Han, Wenning Yang, Guopeng Wang, Jing Wang, Xiaoquan Jiang, Muli Sen, Xueyan Li, Guohua Yu, Yuanyuan Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Nutrition
Subjects:
Paeoniae Radix Alba
non-alcoholic fatty liver disease
sequential metabolism
UPLC-Q Exactive Orbitrap HRMS
surface plasmon resonance
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2021.677659/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2021.677659/full

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