DNAJB6 suppresses alpha-synuclein induced pathology in an animal model of Parkinson's disease

Background: α-synuclein (α-syn) aggregation can lead to degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) as invariably observed in patients with Parkinson's Disease (PD). The co-chaperone DNAJB6 has previously been found to be expressed at higher levels in PD pa...

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Bibliographic Details
Main Authors: Sertan Arkan, Mårten Ljungberg, Deniz Kirik, Christian Hansen
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121002266