Profiling of Naturally Occurring Antibodies to the Thomsen-Friedenreich Antigen in Health and Cancer: The Diversity and Clinical Potential
The Thomsen-Friedenreich (TF) antigen is expressed in a majority of human tumors due to aberrant glycosylation in cancer cells. There is strong evidence that humoral immune response to TF represents an effective mechanism for the elimination of cancer cells that express TF-positive glycoconjugates....
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Format: | Article |
Language: | English |
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Hindawi Limited
2020-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2020/9747040 |