A Broad and Potent H1-Specific Human Monoclonal Antibody Produced in Plants Prevents Influenza Virus Infection and Transmission in Guinea Pigs

A Broad and Potent H1-Specific Human Monoclonal Antibody Produced in Plants Prevents Influenza Virus Infection and Transmission in Guinea Pigs

Although seasonal influenza vaccines block most predominant influenza types and subtypes, humans still remain vulnerable to waves of seasonal and new potential pandemic influenza viruses for which no immunity may exist because of viral antigenic drift and/or shift. Previously, we described a human m...

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Bibliographic Details
Main Authors: Jun-Gyu Park, Chengjin Ye, Michael S. Piepenbrink, Aitor Nogales, Haifeng Wang, Michael Shuen, Ashley J. Meyers, Luis Martinez-Sobrido, James J. Kobie
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Viruses
Subjects:
orthomyxovirus
influenza virus
antivirals
plantibody
prophylactic
therapeutic
monoclonal antibody
antibody treatment
neutralizing antibody
virus infection
virus transmission
Online Access:https://www.mdpi.com/1999-4915/12/2/167

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https://www.mdpi.com/1999-4915/12/2/167

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