Current approaches towards quantitative mapping of the interactome

Protein-protein interactions (PPIs) play a key role in many, if not all, cellular processes. Disease is often caused by perturbation of PPIs, as recently indicated by studies of missense mutations. To understand the associations of proteins and to unravel the global picture of PPIs in the cell, diff...

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Bibliographic Details
Main Authors: Alexander eBuntru, Philipp eTrepte, Konrad eKlockmeier, Sigrid eSchnoegl, Erich E. Wanker
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Genetics
Subjects:
PLA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00074/full