Genetic variants of the EGFR ligand-binding domain and their association with structural alterations in Arab cancer patients

Genetic variants of the EGFR ligand-binding domain and their association with structural alterations in Arab cancer patients

Abstract Objective This study aimed to identify novel genetic variants in the CR2 extracellular domain of the epidermal growth factor receptor (EGFR) in healthy individuals and patients with six different types of adenocarcinoma, in Arabian peninsula populations. It also aimed to investigate the eff...

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Bibliographic Details
Main Authors: Maryam Marzouq, Ali Nairouz, Noureddine Ben Khalaf, Sonia Bourguiba-Hachemi, Raed Quaddorah, Dana Ashoor, M. Dahmani Fathallah
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Research Notes
Subjects:
EGFR protein
Missense mutation
Arabs
Adenocarcinoma
Single nucleotide polymorphism
CR1/CR2 EGFR domains
Online Access:https://doi.org/10.1186/s13104-021-05559-y

Internet

https://doi.org/10.1186/s13104-021-05559-y

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