Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification

Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification

Mice that overexpress human apolipoprotein C-I (apoC-I) homozygously (APOC1+/+ mice) are protected against obesity and show cutaneous abnormalities. Although these effects can result from our previous observation that apoC-I inhibits FFA generation by LPL, we have also found that apoC-I impairs the...

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Bibliographic Details
Main Authors: Marit Westerterp, Jimmy F.P. Berbée, Dianne J.M. Delsing, Miek C. Jong, Marion J.J. Gijbels, Vivian E.H. Dahlmans, Erik H. Offerman, Johannes A. Romijn, Louis M. Havekes, Patrick C.N. Rensen
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Journal of Lipid Research
Subjects:
lipoprotein
macrophage
skin
lipoprotein lipase
triglyceride
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520425635

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http://www.sciencedirect.com/science/article/pii/S0022227520425635

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