Does malaria affect placental development? Evidence from in vitro models.

BACKGROUND:Malaria in early pregnancy is difficult to study but has recently been associated with fetal growth restriction (FGR). The pathogenic mechanisms underlying malarial FGR are poorly characterized, but may include impaired placental development. We used in vitro methods that model migration...

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Bibliographic Details
Main Authors: Alexandra J Umbers, Danielle I Stanisic, Maria Ome, Regina Wangnapi, Sarah Hanieh, Holger W Unger, Leanne J Robinson, Elvin Lufele, Francesca Baiwog, Peter M Siba, Christopher L King, James G Beeson, Ivo Mueller, John D Aplin, Jocelyn D Glazier, Stephen J Rogerson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3561386?pdf=render