External contamination in single cell mtDNA analysis.

Mitochondrial DNA (mtDNA) variation in single hematopoietic cells, muscle fibers, oocytes, and from tiny amount of tumor tissues and degraded clinical specimens has been reported in many medical publications. External DNA contamination, notoriously difficult to avoid, threatens the integrity of such...

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Bibliographic Details
Main Authors: Yong-Gang Yao, Hans-Jürgen Bandelt, Neal S Young
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1930155?pdf=render