Microbial metabolism shifts towards an adverse profile with supplementary iron in the TIM-2 in vitro model of the human colon

Microbial metabolism shifts towards an adverse profile with supplementary iron in the TIM-2 in vitro model of the human colon

Oral iron administration in African children can increase the risk for infections. However, it remains unclear to what extent supplementary iron affects the intestinal microbiome. We here explored the impact of iron preparations on microbial growth and metabolism in the well-controlled TNO’s in vitr...

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Bibliographic Details
Main Authors: Guus A.M. Kortman, Bas E. Dutilh, Annet J.H. Maathuis, Udo F Engelke, Jos eBoekhorst, Kevin P Keegan, Fiona Gwendolyn Ginn Nielsen, Jason eBetley, Jacqueline C Weir, Zoya eKingsbury, Leo A.J. Kluijtmans, Dorine W Swinkels, Koen eVenema, Harold eTjalsma
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Microbiology
Subjects:
Metabolome
Metagenome
Toxicity
Microbial metabolism
gut microbiome
proteolytic activity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01481/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01481/full

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